CVE-2026-31973— NULL pointer dereference in samtools cram-size
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I. Basic Information for CVE-2026-31973
Vulnerability Information
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Vulnerability Title
NULL pointer dereference in samtools cram-size
Source: NVD (National Vulnerability Database)
Vulnerability Description
SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Source: NVD (National Vulnerability Database)
CVSS Information
N/A
Source: NVD (National Vulnerability Database)
Vulnerability Type
空指针解引用
Source: NVD (National Vulnerability Database)
Vulnerability Title
samtools 代码问题漏洞
Source: CNNVD (China National Vulnerability Database)
Vulnerability Description
samtools是samtools开源的一个处理高通量测序数据的工具集。 samtools 1.23.1之前版本、1.22.2之前版本和1.21.1之前版本存在代码问题漏洞，该漏洞源于cram-size命令缺少错误检查，可能导致空指针取消引用。
Source: CNNVD (China National Vulnerability Database)
CVSS Information
N/A
Source: CNNVD (China National Vulnerability Database)
Vulnerability Type
N/A
Source: CNNVD (China National Vulnerability Database)
Affected Products
II. Public POCs for CVE-2026-31973
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Same Patch Batch · samtools · 2026-03-18 · 12 CVEs total
| CVE-2026-31962 | HTSlib CRAM reader has heap buffer overflow due to improper validation of input | |
| CVE-2026-31964 | HTSlib CRAM decoder has a NULL Pointer Dereference | |
| CVE-2026-31963 | HTSlib CRAM reader has heap buffer overflow due to improper validation of input | |
| CVE-2026-31965 | HTSlib CRAM reader has out-of-bounds reads due to improper validation of input | |
| CVE-2026-31966 | HTSlib CRAM reader has out-of-bounds read due to improper validation of input | |
| CVE-2026-31967 | HTSlib CRAM reader has out-of-bounds read due to improper validation of input | |
| CVE-2026-31968 | HTSlib CRAM decoder vulnerable to buffer overflow | |
| CVE-2026-31971 | HTSlib CRAM decoder vulnerable to buffer overflow | |
| CVE-2026-31969 | HTSlib CRAM decoder has a heap buffer overflow | |
| CVE-2026-31970 | HTSlib BGZF index file reader has a heap buffer overflow | |
| CVE-2026-31972 | samtools mpileup has use-after-free leading to an invalid read |
IV. Related Vulnerabilities
Same vendor: samtools
- CVE-2026-31972
samtools mpileup has use-after-free leading to an invalid re - CVE-2026-31971
HTSlib CRAM decoder vulnerable to buffer overflow - CVE-2026-31970
HTSlib BGZF index file reader has a heap buffer overflow - CVE-2026-31969
HTSlib CRAM decoder has a heap buffer overflow - CVE-2026-31968
HTSlib CRAM decoder vulnerable to buffer overflow
Same weakness: CWE-476
- CVE-2026-8252
Open5GS SMF smf_nsmf_handle_create_data_in_hsmf null pointer - CVE-2026-7259
Null pointer dereference in php_mb_check_encoding() via mb_e - CVE-2026-7262
NULL pointer dereference in SOAP apache:Map decoder with mis - CVE-2026-42183
Argo Workflows: SSO RBAC Delegation Nil Pointer Dereference - CVE-2026-6666
PgBouncer crash in kill_pool_logins_server_error
V. Comments for CVE-2026-31973
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