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CVE-2026-31967— HTSlib CRAM reader has out-of-bounds read due to improper validation of input

EPSS 0.02% · P7
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I. Basic Information for CVE-2026-31967

Vulnerability Information

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Vulnerability Title
HTSlib CRAM reader has out-of-bounds read due to improper validation of input
Source: NVD (National Vulnerability Database)
Vulnerability Description
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Source: NVD (National Vulnerability Database)
CVSS Information
N/A
Source: NVD (National Vulnerability Database)
Vulnerability Type
跨界内存读
Source: NVD (National Vulnerability Database)
Vulnerability Title
HTSlib 输入验证错误漏洞
Source: CNNVD (China National Vulnerability Database)
Vulnerability Description
HTSlib是samtools开源的一个C语言的库文件。 HTSlib 1.23.1之前版本、1.22.2之前版本和1.21.1之前版本存在输入验证错误漏洞,该漏洞源于cram_decode_slice函数中未验证配对参考ID字段,可能导致越界数组读取。
Source: CNNVD (China National Vulnerability Database)
CVSS Information
N/A
Source: CNNVD (China National Vulnerability Database)
Vulnerability Type
N/A
Source: CNNVD (China National Vulnerability Database)

Affected Products

VendorProductAffected VersionsCPESubscribe
samtoolshtslib < 1.21.1 -

II. Public POCs for CVE-2026-31967

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III. Intelligence Information for CVE-2026-31967

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Same Patch Batch · samtools · 2026-03-18 · 12 CVEs total

CVE-2026-31962HTSlib CRAM reader has heap buffer overflow due to improper validation of input
CVE-2026-31964HTSlib CRAM decoder has a NULL Pointer Dereference
CVE-2026-31963HTSlib CRAM reader has heap buffer overflow due to improper validation of input
CVE-2026-31965HTSlib CRAM reader has out-of-bounds reads due to improper validation of input
CVE-2026-31966HTSlib CRAM reader has out-of-bounds read due to improper validation of input
CVE-2026-31968HTSlib CRAM decoder vulnerable to buffer overflow
CVE-2026-31971HTSlib CRAM decoder vulnerable to buffer overflow
CVE-2026-31969HTSlib CRAM decoder has a heap buffer overflow
CVE-2026-31970HTSlib BGZF index file reader has a heap buffer overflow
CVE-2026-31973NULL pointer dereference in samtools cram-size
CVE-2026-31972samtools mpileup has use-after-free leading to an invalid read

IV. Related Vulnerabilities

V. Comments for CVE-2026-31967

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